The Digital Revolution in Microscopy
Lyncée Tec is a fast growing, customer-oriented and market-driven young company.
Professor Christian Depeursinge , co-founder, president of Lyncée Tec SA scientific board, holds a PhD in Physics and is the leader of Microvision and Microdiagnostic group (MVD) in the Institute of Applied Optics (IOA) at EPFL. He has, initiated the DHM™ technology development at EPFL. He is former President of the Swiss Society of Bioengineering. He has been honoured with numerous prizes; he received in particular the lecture Award of the European Microscopy Society in 2002 for the DHM™ technique.
He has conducted 16 PhD students, has directed more than ten project of technology transfers with various industries in the medical and optoelectronic fields. He is the author of over 72 articles published in peer reviewed journals and has given numerous invited lectures. He has patented 9 inventions. He gave numerous courses; in particular has animated and coordinated the University "Enterprise Training Partnership European project Comett II: UETP Euro-BME (European Biomedical Engineering Partnership)", has given courses in the frame of the European Program for Training , and of the postgraduate Course on Coherent Imaging (Doctoral School). Currently, he gives speciality course on Optical Design at EPFL.
His current research interest is microscopy, in particular Digital Holographic Microscopy, and more generally "Coherence Imaging Techniques" applied in particular in nanotechnique, nano-diagnostics and nano-assembly in biology, living tissues analysis and spectroscopy and "in vivo biopsy" techniques.
Professor Pierre Magistretti , co-founder, vice president of Lyncée Tec SA scientific board, is 52 year-old; he has received his MD from the University of Geneva and his PhD from the University of California at San Diego, while working at the Salk Institute with Dr Floyd E. Bloom. He has been awarded the START career development award from Swiss National Science Foundation (1987-1888). He is the recipient of the 1997 Theodore-Ott Prize of the Swiss Academy for Medical Sciences. In 2001 Pierre J. Magistretti was elected member of Academia Europeae (Physiology and Medicine), in 2002 he was awarded the Emil Kraepelin Professorship of the Max-Planck Institute of Psychiatry in Münich, and in 2003 he has been elected ad personam member of the Swiss Academy of Medical Sciences.
Positions occupied by Pierre J. Magistretti include among other: Professor of Physiology (1988-2004), Co-Chairman and Chairman of the Department of Physiology (2001-2004) , Vice-Dean of the University of Lausanne Medical School (1996 - 2000) and President of the Federation of European Neuroscience Societies (FENS) (2002-2004) which has a membership of over 15000 european neuroscientists. He is or has been member of numerous other international scientific advisory boards and president of several societies. He is presently Director of the Center for Psychiatric Neuroscience at the University of Lausanne Medical School (since 2002) and Professor of Neuroscience and Co-Director at the Brain and Mind Institute (BMI), EPFL (since 2005). He is also member of the National Council for research: the Swiss National Science Foundation.
Pierre J. Magistretti has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain. This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurologic and psychiatric research. The group directed by Pierre J. Magistretti consists of 20 scientists, over two thirds of which are supported by grants awarded on a peer-review basis (eg Swiss National Science Foundation, European Community, Human Frontier Science Organization)). He is the author of over 150 articles published in peer reviewed journals and of numerous books chapters. He is in author with F. Ansermet of the book: "A chacun son cerveau. Plasticité neuronale et inconscient", Ed. Odile Jacob, Paris. Over the last five years he has given over 100 invited lectures at international meetings or at universities in Europe and North America.
Pierre Marquet, co-founder, secretary of Lyncée Tec SA scientific board, has received his Master in physics from the Swiss Federal Institute of Technology in 1991 and his MD-PhD from the University of Lausanne. He has been awarded the MD-PhD fellow from the Swiss National Science Foundation (1998-2001) and is the recipient of the "Prix jeune chercheur européen 2001 de la société française des Laser médicaux".
He has been active since many years in the developments of new optical imaging techniques (spectroscopy, coherent and non-coherent imaging techniques) dedicated to improve our comprehensive understanding of brain functions. In particular, he has achieved seminal work which has allowed the utilization of digital holography as a new 3D microscopy technique in the field of life science. He is teaching biomedical engineering post-graduate course on cellular imaging at the Swiss Federal Institute of Technology. Currently, he is group leader in the Prof. P. J. Magistretti's research team at the EPFL.
Ramiro Conde, member of Lyncée Tec SA scientific board, PhD, specialized in optics, has completed his cursus with the Comett Euro-BME course on Minimum-Invasive Intervention Techniques and with the Medical Imaging Postgraduate course on Biomedical Engineering (EPFL). His has conducted two technology transfer projects in the medical field.
He is co-inventor of two patents and has several reviewed publications in international scientific journals.
He is working presently in the microsystem industry where he is responsible for a diffractive element development group. He brings to Lyncée Tec SA its network as well as an extensive experience of quality control of micro-optical elements and assembly of micro-opto-mechanical systems.
Jean-Yves Chatton , member of Lyncée Tec SA scientific board, PhD, has been active for many years using several approaches of quantitative optical microscopy, including confocal microscopy. His research has spanned fields such as transport physiology, intracellular second messenger signaling, pharmacology, neuron-glia interactions. He is teaching optical and fluorescence microscopy at the University of Lausanne, Medical School, as well as co-organizing a biomedical engineering post-graduate course on cellular imaging. He has recently been appointed as coordinator of the Cellular Imaging Facility at Lausanne University. He is also the secretary of the Swiss Society of Pharmacology and Toxicology .
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